Natural 5-Htp 99% Capsules for Mood and Relaxation

• Certification: Hala
• Assay Method: HPLC
• Application Form: Injection, Lotion, Suppository, Paste, Tablet, Capsule
• Model NO.: JT-345
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Ghanaian Seed Extract
• Transport Package: 25kgs/Drum or Carton, Inner by Aluminum Foil Bag
• Specification: 99%
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg/Month

Product Description

Product name	5-hydroxytryptophan
Appearance	White crystalline powder
CAS	56-69-9
Test Method	HPLC
Molecular Formula	C11H12N2O3
Molecular Weight	220.225

5-hydroxytryptophan
5-hydroxytryptophan (5-HTP) is an amino acid substance. It can serve as a precursor substance for 5-hydroxytryptamine (serotonin, 5-HT) in the human body (and subsequently as a precursor substance for melatonin). Some double-blind studies have shown that 5-HTP can increase the concentration of serotonin in the brain, improve depression, promote the formation of melatonin, improve sleep quality, and suppress appetite. However, these studies have some problems. Therefore, more research is still needed to confirm whether 5-HTP has these physiological effects. [1] The seeds of the Ghanaian plant contain abundant 5-hydroxytryptophan, which is the main natural source for manufacturing 5-HTP.
Specification:  99%

5-Hydroxy-L-tryptophan is an aromatic amino acid naturally produced by the body from the essential amino acid l-tryptophan. 5-Hydroxy-L-tryptophan is the immediate precursor of the neurotransmitter serotonin. The conversion to serotonin is catalyzed by the enzyme aromatic l-amino acid decarboxylase (EC 4.1.1.28, AADC1 also known as dopa decarboxylase), an essential enzyme in the metabolism of the monoamine neurotransmitters. An accumulation of 5-Hydroxy-L-tryptophan in cerebrospinal fluid occurs in Aromatic l-amino acid decarboxylase deficiency (OMIM 608643), accompanied by an increased excretion in the urine of the patients, which are indicative of the disorder but not specific 5-Hydroxy-L-tryptophan is also increased in other disorders such as in Parkinson's patients with severe postural instability and gait disorders. Confirmation of the diagnosis AADC deficiency is then required by enzyme activity measurement or genetic analysis. The amount of endogenous 5-Hydroxy-L-tryptophan available for serotonin synthesis depends on the availability of tryptophan and on the activity of various enzymes, especially tryptophan hydroxylase (EC 1.14.16.4), indoleamine 2,3-dioxygenase (EC 1.13.11.52), and tryptophan 2,3-dioxygenase. (EC 1.13.11.11, TDO). 5-Hydroxy-L-tryptophan has been used clinically for over 30 years. In addition to depression, the therapeutic administration of 5-Hydroxy-L-tryptophan has been shown to be effective in treating a wide variety of conditions, including fibromyalgia, insomnia, binge eating associated with obesity, cerebellar ataxia, and chronic headaches. 5-Hydroxy-L-tryptophan easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin. Supplementation with 5-Hydroxy-L-tryptophan is hypothesized to normalize serotonin synthesis, which is putatively related to its antidepressant properties. (A3384, A3385, A3386).