Premium L-Citrulline Nitrate Powder for Enhanced Athletic Performance

• CAS No.: 223253-05-2
• Formula: C6h14n4o6
• EINECS: 206-759-6
• Model NO.: JT-443
• Resource: Chemosynthesis
• MW: 238.19856
• Transport Package: 25kgs/Drum or Carton, Inner by Aluminum Foil Bag
• Specification: 99%
• Trademark: JT
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg/Month

Product Description

Product name	L-Citrulline Nitrate
Appearance	White crystalline powder
CAS	372-75-8
Test Method	HPLC
Chemical Formula	C6H14N4O6
Molecular Weight	175.19

Citrulline, also known as aminoformylornithine in Chinese, has the chemical name L-Citrulline. Its chemical formula is CHNO, with a molecular weight of 175.19 and the CAS number 372-75-8. The pure form is a white columnar crystal with a melting point of 235.5ºC. It is soluble in water but insoluble in ethanol and ether. In 1914, Japanese scholar Katsuto Okada first isolated it from watermelons and melons, and it was later confirmed by Katsutoshi Watanabe [2] [11] [29].
This substance is mainly found in the fruits of cucurbit crops such as watermelons and melons, as well as the wood of Japanese birch trees. The content of citrulline in watermelons ranks first among cucurbit crops, with yellow fleshed watermelons having a higher content than red fleshed ones [1] [10] [24]. It is synthesized in the urea cycle from ornithine and carbamoyl phosphate, and since the ASS and ASL enzymes that catalyze the decomposition have low activity in the intestine, it is released directly into the blood without decomposition. It can also be a by-product of arginine converting to nitric oxide [4-5] [14]. Production methods include extraction and separation, chemical synthesis, fermentation, and microbial enzyme methods. Among them, the microbial enzyme method has a high product purity and no D-type optical isomers [2] [7] [11] [13]. Detection methods mainly include high-performance liquid chromatography and spectrophotometry [3] [20]. The normal value in serum is 20-40 μmol/L. An abnormal increase suggests citrulline hyperemia [6] [27-28].
It is used clinically for the diagnosis of rheumatoid arthritis and the assessment of sepsis treatment. Its pharmacological effects cover antioxidant defense (removing hydroxyl free radicals), increasing arginine levels to promote NO synthesis, enhancing immunity, delaying aging, and improving heart and lung function. It has an improving effect on male sexual dysfunction and radiation-induced intestinal damage, and is widely used in the fields of medicine, health care, and food.
Specification:  99%

Antioxidation and anti-aging
By eliminating free radicals in the human body through antioxidants and other means, a certain degree of aging delay can be achieved. Studies have shown that citrulline can eliminate hydroxyl free radicals and alleviate tissue damage caused by free radicals during ischemia, hypoxia, and stress. [25] Systematic studies have shown that citrulline has the effects of reducing cellular aging, protecting DNA from damage, preventing cell cycle arrest, regulating macrophage metabolism, and reducing inflammation. Long-term supplementation of citrulline in elderly mice can produce beneficial effects and improve age-related phenotypes. [26]
Enhancing muscle strength and endurance
Since citrulline serves as a precursor for the synthesis of arginine, it can be converted into arginine in many tissues. Taking citrulline can effectively improve the body's anti-fatigue ability, maintain healthy heart and lung functions, improve mental clarity, reduce stress and overcome depressive emotions, balance blood sugar concentration, enhance muscle strength, improve physical fitness, and has a good effect in sports health care. [14]
Preventing male diseases and improving sexual function
Studies have shown that citrulline has a significant effect in preventing and treating prostate diseases, including prostatitis, prostate swelling, prostate hypertrophy, prostate hyperplasia, and prostate cancer. In addition, citrulline can cause the human body to produce nitric oxide, which can improve male sexual ability. Moreover, citrulline can be fully absorbed with relatively small side effects.