Minoxidil Hair Loss Medicine Health Care Products

• Certification: Hala
• Assay Method: HPLC
• Application Form: Injection, Lotion, Suppository, Paste, Tablet, Capsule
• Model NO.: JT-385
• Application: Health Care Products, Medicine
• State: Powder
• Transport Package: 25kgs/Drum or Carton, Inner by Aluminum Foil Bag
• Specification: 99%
• Trademark: JT
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg/Month

Product Description

Product name	Minoxidil
Appearance	White crystalline powder
CAS	38304-91-5
Test Method	HPLC
Chemical Formula	C9H15N5O
Molecular Weight	209.248

Minoxidil
Minoxidil, also known as Minolide or Changpaide, is an organic compound. Its chemical name is 6-(1-piperidinyl)-2,4-pyrimidine diamine-3-oxide, with the chemical formula C9H15N5O, [5] and its molecular weight is approximately 209.25. This substance is a white or off-white crystalline powder, slightly soluble in ethanol, slightly soluble in water, extremely slightly soluble in acetone, and soluble in glacial acetic acid; [6]
There are many synthesis methods for minoxidil. The synthetic route shown below is more suitable for industrial production. The first step: Use ethyl cyanoacetate and guanidine hydrochloride as raw materials, and undergo a cyclization reaction under the action of a base; the second step: Use trichlorophosphine for chlorination, and transfer the product to the organic phase through extraction; the third step: Under the action of 2-chloro-4-oxophenylbenzoic acid, the N on the pyrimidine ring undergoes an oxidation reaction to obtain the N oxide; the fourth step: The N oxide reacts with piperidine, and the piperidine acts as a solvent for the reflux reaction to obtain it. [7] Minoxidil is mainly used as a blood pressure-lowering drug, for stubborn, primary or renal hypertension, and can also be used to prevent oily hair loss and in the livestock industry. Clinically, it is used as a potassium ion channel opener, which can directly relax vascular smooth muscle, has a strong effect on small artery dilation, reduces peripheral resistance, lowers blood pressure, and has no effect on capacity vessels, thus promoting venous return. At the same time, due to the reflexive regulatory effect and positive frequency effect, it can increase cardiac output and heart rate, but does not cause orthostatic hypotension. [5] The approved dosage forms of minoxidil in China include ointment, spray, gel, tincture, tablet, foam, etc.
Specification:  99%

Minoxidil has the functions of lowering blood pressure, promoting hair growth, stimulating the skin, improving hair loss, and treating seborrheic dermatitis.
1. Lowering blood pressure
Minoxidil is a type of peripheral vasodilator. When used topically for a long period of time, it can stimulate hair growth in patients with male pattern baldness and alopecia areata.
2. Promote hair growth
Minoxidil can promote hair growth and is commonly used in clinical practice to treat conditions such as male pattern baldness and alopecia areata.
3. Stimulate the skin
Minoxidil can dilate blood vessels, increase blood flow to the skin, promote skin metabolism, thereby stimulating the skin, enhancing its elasticity, and reducing the formation of wrinkles.
4. Improve hair loss
Minoxidil can enhance blood circulation in the scalp, alleviate hair loss symptoms, and also reduce dandruff.
5. Treating seborrheic dermatitis
Seborrheic dermatitis is a common chronic superficial and inflammatory skin disease, which is frequently seen on the head, face, chest, and back, etc. The main symptoms include redness, desquamation, and itching. Patients can follow the doctor's advice to use minoxidil for treatment. It can stimulate the dilation of skin capillaries, increase the blood flow in the skin, and improve the situation of excessive sebum secretion, thereby treating seborrheic dermatitis.