Cosmetics Grade L-Ergothioneine Antioxidant Effect CAS 497-30-3

• Certification: Hala
• Assay Method: HPLC
• Application Form: Injection, Lotion, Suppository, Paste, Tablet, Capsule
• Model NO.: JT-311
• Application: Health Care Products, Medicine
• State: Crystal
• CAS: 497-30-3
• Transport Package: 25kgs/Drum or Carton, Inner by Aluminum Foil Bag
• Specification: 1% 99%
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000kg/Month

Product Description

Product name	L-Ergothioneine
Appearance	White crystalline powder
CAS	497-30-3
Test Method	HPLC
Molecular Formula	C9H15N3O2S
Molecular Weight	229.3

L-Ergothioneine
Ergothionein is a natural antioxidant, which can protect cells in the human body and is an important active substance in the body. Natural antioxidants are safe and non-toxic and have become a research hotspot. Ergothionein, as a natural antioxidant, has come into people's sight. It has many physiological functions, such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal cell growth and cellular immunity.
Specification:  1%  99%
1.Antioxidant effect
Ergothionine is a natural amino acid derived from plants and can be accumulated in animals. Studies have shown that it has the effect of antioxidant. It can effectively remove -OH, chelate divalent iron and copper ions, and prevent the formation of -OH from H2O2 under the action of iron ions or copper ions. It also inhibits the cupr-dependent oxidation of oxyhemoglobin and inhibits the peroxidation of arachidonic acid that occurs when myoglobin (or hemoglobin) is mixed with H2O2. Ergothionein also potent scavengers hypochlorous acid, thereby preventing inactivation of a 1 -antiprotease. However, it does not inhibit the peroxidation of lipid particles in the presence of iron ions. AKanmu D et al. showed that ergothionein at a certain concentration present in the body can act as an antioxidant.
2.Protective effect on cells
Ergothionein is a powerful hypochlorous acid scavenger (HOCl). Although many compounds can react with hypochlorous acid, few react as quickly as ergothionein. a 1 -antiprotease inhibitors (apis), such as elastase, are particularly sensitive to hypochlorous acid, and ergothionine at physiological concentrations is highly effective in protecting apis from hypochlorous acid-induced inactivation, since neutrophils are the main source of hypochlorous acid in the body, One of the effects of ergothionein is to protect red blood cells from receiving damage from neutrophils from sites of normal functioning or morbid inflammation.
3.Anti-inflammatory effect
Peroxynitrite (PERoxynitrite) is endogenously produced as a limited diffusion reaction of NO and superoxide and is a potent oxidant involved in the pathophysiology of inflammation, such as ischemia-reperfusion injury, atherosclerosis, acute pneumonia and sepsis. Ergothionein can inhibit peroxynitrite anion-mediated oxidation of amino acids, such as the nitrification of tyrosine, thus providing feasibility for the treatment of inflammation.